Medicine in a Nutshell

Sunday, November 1, 2009

Sickle Cell Disease (SCD)

Hemoglobin
2 Mutant Beta-Globulins (2 Wild Type Alpha-Gb)
11q6 SNP A to T; glutamate to valine

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Content: Robust 3-D Diagnoses

Diagnoses:

1. 3-dimensional

2. succinct

3. robust

3-dimensions:

1. anatomical localization

2. pathological lesion

3. etiological process

Succinct:

1. single line per dimension

2. clear

3. symptomatology implied

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Overarching Mission

1. diagnostic precision

2. reveal uncertainty & differentials

3. inspire smart prescription

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  - A Ca++ Channel